Comments by J. C. Spencer

Victor A. McKusick died last Tuesday (July 22, 2008). Without the genetics pioneer work of Victor A. McKusick, glycomics would be an operating system (OS) without a program to run on it. His work will help drive medical science from now on. He was the FATHER OF MEDICAL GENETICS. In the late 1960s, he proposed that all the human genes be mapped to the individual chromosomes in their own specified order, it was an idea that seemed preposterous, difficult and boring. Peter Goodfellow, a distinguished English geneticist, said last year, "He was the one on the planet who held the faith and who thought that it was actually worthwhile to map the genes.

Now the story of Victor A. McKusick

A Genetics Pioneer Who Mapped the Inner World

Comments by J. C. Spencer

We have learned that misfolding of proteins is the cause or contributing factor for neurodegenerative diseases.  Proteins overexpressed in ways outside the normal seem to be the triggering factor that causes cancer.
Weak or false glycoptrotein signals is the cause for misfolding or overexpressing of protein.  New research on malignant melanoma at University of Rochester targets a specific protein.

Here is the report.  The Abstract of the Study follows the report by ScienceDaily.

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University of Rochester Medical Center researchers found a new protein produced excessively in malignant melanoma, a discovery that is particularly relevant as skin cancer rates climb dramatically among young women.

The protein, IMP-3, is not over-expressed in harmless moles but is increased in the most dangerous types of skin cancer,

Healthcare costs are a major danger to families, companies, and in fact, the country as a whole. The two factors that are a danger to our economy are HEALTHCARE and ENERGY. I am convinced that as we put our focus on healthcare (instead of sickness care) WE CAN LOWER COSTS along the same pathway that computer technology has been lowered. Over the last number of years while there have been great advances in computer technology, the costs of that technology has come down.

My first computer did not even have a hard drive and cost (if I recall correctly) around $10,000. It was a console and operated with two large floppy drives. The first hard drive computer I bought was 10 Mega bytes (Mb) and the salesman told me that I would never fill it. Now we are dealing in really big bytes: gygabytes, terabytes, and petabytes. If computer scientists had continued to think in the same box they were thinking in when I bought my first computer, we would all be living in that same very expensive box. The plan was to always improve the technology, make it better for less money.

An entirely new finding.

Comments by J. C. Spencer

We know that the HIV cannot replicate on its own and must rely on the host cell to reproduce. HIV infects helper T cells with a protein embedded in its envelope called gp120. The gp 120 protein binds to a molecule called CD4 on the surface of the helper T cell. This process initiates a complex set of reactions that transfers the HIV genetic code into the host cell.

Comments by J. C. Spencer

Measuring specific sugars on the surface of cells is the future of diagnostic medicine because that will determine how healthy the cells are. Counting these different sugars that are the building blocks for glycoprotein receptor sites is the latest breakthrough in GLYCOMICS. A new sugar counting method can lead to developing wellness biomarkers. Determine the health of your cells and you determine your wellness. The number of glycoproteins on the surface of a cell indicates the health of the cell. This test may provide the data for discovering if a person has early stages of cancer or potentially any other disease. Cancer is the first disease to be diagnosed with this new test. The reason cancer is the first of many tests is that we have known for years that cancer cells are not covered with the glycoprotein receptor sites like healthy cells. The ability to count these sugars on the cells is paramount in early detection of diseases.

Comments by J. C. Spencer

A new fast-advancing dementia has just been discovered with additional symptoms such as the loss of the ability to speak and move. Misfolded proteins wreak havoc with the brain. Neurodegenerative diseases are caused by these misshaped proteins. Healthy glycoproteins make possible the communication for all cells. Glycomics is the OS (operating system) for the genome. Vital sugars are the building blocks for glycoproteins. Unhealthy cells are vulnerable to fast decay.

New Fast-Advancing Dementia Discovered in US

A new form of Creutzfeldt-Jakob disease (CJD) may have been uncovered in a handful of patients in the US.

Comments by J. C. Spencer

It is a well known medical fact that it is the toxic beta amyloid 40 and 42 protein that destroys vital connections in brain cells that causes Alzheimer’s.  It is also a well known scientific fact that a highly functional immune system can prevent Alzheimer’s.  I am delighted to see scientists all over the world working to prevent, delay, or totally cure Alzheimer’s.  The more information we can gather, the better the opportunity to prevent, delay, or cure this awful brain disease.  Out of the UK comes this report of a possible tomato “vaccine” that could prevent Alzheimer’s.  The results seem to be quite similar to the paper about the healthful sugar trehalose altering the gene expression of the beta amyloid 40 and 42 protein in an animal study.

Comments by J. C. Spencer

Physicians, pharmacists, nurses, and a broad range of healthcare professionals have completed our Continuing Medical Education training in glycomics.  Doctors from an impressive number of countries in addition to professionals from Canada and throughout the United States have participated.   It is the objective of The Endowment for Medical Research to educated the professional and general public in the science of glycomics.  While the CME and CEU credits have expired, the same fourteen hour DVD Glycomics Series is still available at a $100 discount in our store front at www.endowmentmed.org.  The science of glycomics is growing at such a rapid rate that there are now 463,471 references posted on the National Library of Medicine website at www.pubmed.gov for glycoprotein.

Today an online pharmacy posted an outstanding article on the boosting of your immune system with glycomics.

Here is their article: