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Glycomics, the science of sugars, play a role in altering gene expression E-mail

Comments by J. C. Spencer

Glycomics, the science of sugars, play a role in altering gene expression as evidenced in research conducted at Texas A&M by David Busbee, PhD, on the faculty of Genetics and Toxicology.  Dr. Busbee presented these studies at two Glycomics Medical Conferences sponsored by The Endowment for Medical Research in Houston.  His presentations are a part of fourteen hours of education in glycomics available on DVD.

Toxins can alter gene expression in very destructive ways while healthful sugars can alter gene expression in a very beneficial way.  Further research is giving us new insight into how to improve brain function and positively alter gene expression.

This morning, a medical doctor friend sent me the following report on how lifestyle changes can trigger genetic changes.  Ways and means of altering gene expression is a major interest here at The Endowment and I believe will be a growing area of interest in healthcare in the years ahead.

Read more...
Melbourne find gives new hope to Huntington's patients E-mail
Comments by J. C. Spencer
Huntington’s disease is affecting more people earlier in life. Weakened immune systems let down the defenses to control this horrible neurodegenerative challenge. The immune systems of HD patients is weaker as the vital sugars are missing from the body. New findings in Australia are reported in tomorrow’s news. The article below was posted tomorrow (international time zone) concerning what they call “the white matter connecting parts of the brain starts breaking down in Huntington’s disease patients well before the crippling symptoms strike.”

Spotting symptoms earlier: researcher India Bohanna with a model of a brain. Picture: Belinda O'Neill We now know what the DNA markers are in Huntington’s patients and in Alzheimer’s patients but these markers do not give us the timing when HD or Alzheimer's will actually strike. That depends on the body’s ability to resist the disease.

Read the science paper Trehalose and beta-amyloid 40 and 42 as in Alzheimer's posted in our Sugar Science Forum and in our NEWS section at www.endowmentmed.org/
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Hidden CDC Data Confirms Vaccine-Autism Link E-mail

Comments by J. C. Spencer

For years I have contended that autism and neurodevelopmental disorders are a result of vaccines containing mercury. Our Nutritional Pilot Surveys using plant sugars have caused us to believe that glycomics holds a potential answer to this health challenge. Go to the NEWS section on the Home Page of The Endowment for Medical Research at www.endowmentmed.org/ and click on Autism for some of my previous newsletters dealing with the subject.

Today the US Autism & Asperger Association announced that hidden CDC data confirms the vaccine link.

Here is the News Release, the Abstract and the Link to the complete hidden paper.

WASHINGTON, DC . A newly published study in the Journal of the Neurological Sciences,[1] the official journal of the World Federation of Neurology,[2] links mercury from the Thimerosal in vaccines with autism and other neurodevelopmental disorders. This study represents six years worth of effort by independent researchers to gain access to hidden US Centers for Disease Control and Prevention data in the Vaccine Safety Datalink.

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Lyme Disease is a Serious Challenge - Doctors Reassess Antibiotics E-mail

Comments by J. C. Spencer
TickLyme disease requires a serious attack especially getting immune system modulated. Eating healthful sugars including the replacement table sugar with trehalose is a good idea when a person has Lyme disease. During the last few years I have issued a number of reports about chronic Lyme disease. My reports along with other Lyme news and information is available on the NEWS section from the Home Page of www.endowmentmed.org/

Can it be that some of the neurodegenerative diseases are really Lyme disease and then manifest into Alzheimer’s, Parkinson’s, and dementia? In our Nutritional Alzheimer’s and Parkinson Pilot Surveys where we used healthful sugars, we discovered 29 patients who tested positive for Lyme disease using the CDC accepted testing.

Lyme disease is normally treated with antibiotics. The information below may be beneficial to a family who has the Lyme challenge. I disagree strongly with the statement in the article that says, “Usually, it's easily cured with a few weeks of antibiotics.”

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High Levels of Glucose Impair Brain Function E-mail

Glucose Comments by J. C. Spencer

The sugar glucose may have a more negative impact on dementia, Alzheimer’s, and other brain functions than previously thought.  A recent UK study shows that the sugar glucose effects cognitive brain function.  While glucose is important for cell function, higher levels of blood glucose were associated with impaired memory performance.

On our thirty minute Conference Call of June 5 (replay available from the Home Page of The Endowment for Medical Research website - www.endowmentmed.org), I discussed briefly how molecules that appear identical may have drastically different function simply because of the bond, the angle of the bond and a series of other possible factors.

Tthe Sugar  Trehalose The healthful sugar trehalose is two glucose molecules bonded together with one molecule turned upside down.  Because this bond is not easily broken, not only does it not seem to impact negatively the sugar levels in the blood or impair memory performance, TREHALOSE APPEARS TO IMPROVE BRAIN FUNCTION.

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Type 1 Diabetes Explained E-mail

Comments by J. C. Spencer

SyringeType 1 diabetes is a growing concern among younger people.  Someone called me this week with grave concerns about a baby born with life threatening diabetes.  Sugar imbalance in your body can be lethal.  The importance of eating healthful sweets cannot be over stated.  We encourage participation in a self funding Pilot Survey.

If you are having any level of success with your diabetes by switching out regular table sugar for the sugar trehalose, please complete the General Public Health Evaluation FORM for Trehalose Nutritional Pilot Survey (For General Public without Huntington’s, Alzheimer’s, or Parkinson’s.)  This Form is available from the Home Page of The Endowment for Medical Research website www.endowmentmed.org

A young man by the name of Tom from the UK has a serious interest in Type 1 diabetes and has compiled and referenced information to help the layperson understand the challenge.

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The Sugar Mannose Verified Beneficial University Study Shows – Sponsored in part by Grant from Finni E-mail

Comments by J. C. Spencer

A new paper out of Finland University of Kuopio associates the sugar mannose with possible prevention of cancers by inhibiting hyaluronan synthesis.  High hyaluronan levels are associated with many human cancers.  Hyaluronan (also 3d Model of the Sugar Mannose called hyaluronic acid or hyaluronate) is a glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues.  It is one of the chief components of the extracellular matrix, contributes significantly to cell proliferation and migration, and may also be involved in the progression of some malignant tumors.

Here is the abstract:
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J. Biol. Chem., Vol. 283, Issue 12, 7666-7673, March 21, 2008

Tiina A., Jokela, Marjo Jauhiainen, Seppo Auriola, Miia Kauhanen, Riikka Tiihonen, Markku I. Tammi, and Raija H. Tammi

Mannose Inhibits Hyaluronan Synthesis by Down-regulation of the Cellular Pool of UDP-N-acetylhexosamines

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Vaccine triggers immune response, prevents Alzheimer's in mice E-mail

Comments by J. C. Spencer

Research in Alzheimer’s and every disease known to man continues to support the fact that modulating the immune system is THE KEY to addressing sickness and disease. The following report out of the University of Rochester Medical Center evidences the lack of amyloid plaque in the brain in mice when the immune response is improved. There is a mad rush to create vaccines to do what nature intended for our bodies to do through proper nutrition. This report supports part of the reason The Endowment for Medical Research had such success with Alzheimer’s patients who participated in the Nutritional Pilot Surveys.

Vaccine triggers immune response, prevents Alzheimer's in mice

Amyloid Peptide A vaccine created by University of Rochester Medical Center scientists prevents the development of Alzheimer’s disease-like pathology in mice without causing inflammation or significant side effects.

Vaccinated mice generated an immune response to the protein known as amyloid-beta peptide, which accumulates in what are called “amyloid plaques” in brains of people with Alzheimer’s. The vaccinated mice demonstrated normal learning skills and functioning memory in spite of being genetically designed to develop an aggressive form of the disease.

 The Rochester scientists reported the findings in an article in the May issue of Molecular Therapy, the journal of The American Society of Gene Therapy.

Read more...
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