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Trehalose helping in diabetes, triglycerides, kidney diseases, and neurodegenerative diseases? E-mail
Untitled Document

Can trehalose play a role in helping diabetes, triglycerides, kidney diseases, and neurodegenerative diseases? We are seeking the answer.
Comments by J. C. Spencer:

We are in the early stages of our Sugar Pilot Surveys and what we are discovering is encouraging. Obviously more research is needed. Some diabetics are monitoring their own blood sugar levels and reporting to us they appear more normal as long as they are eating trehalose. When they stop using trehalose, the sugar load escalates. We are receiving wide spread reports of essential tremors diminishing or ceasing while using trehalose. One family gave us an antidotal report of the husband with tremors of the mouth that made eating very difficult. The wife placed a quarter teaspoon of trehalose under his tongue and the tremors stopped almost immediately.

The following abstract of a science paper references trehalose, macronutrient storage, insulin-like receptors, diabetes, triglycerides, and neurodegenerative diseases. To say the least, for all of these to be referenced in one paper is rather astounding. I do not pretend to fully understand what all this means. But, I openingly contend that it is interesting.

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Neurological Disorders May be Caused by Defective Calcium Metabolism E-mail
Neurological Disorders May be Caused by Defective Calcium Metabolism

Comments by J. C. Spencer

Deranged calcium signaling is caused by disruptive calcium flow within nerve cells. Cell-to-cell communication and intra-cellular communication is the cause for neurodegenerative diseases. Abnormal calcium release is toxic to cells and results in impaired motor function, said Dr. Ilya Bezprozvanny, professor of physiology at UT Southwestern and senior author of the study published in the Nov. 26 issue of the Journal of Neuroscience.

I discuss defective calcium metabolism in my book Expand Your Mind - Improve Your Brain in Chapter 32 entitled Age well - He who finishes last, finishes well. Concerning calcium metabolism I stated, “Usually the enzym calpain, which depends on calcium for its activity, keeps the buildup of protein down. So, inadequate dietary calcium means that too much protein can build up because there is not enough calpain to keep the synapses clean. Unfortunately, an excess of calcium in the diet also creates a problem because the calpain may start to interfere with proper neural transmissions. Calpain can be an enemy of proper brain function when it is not regulated. Proper calcium balance in the brain is vital.”

Moderation in all things produces better brain health and that includes proper intake of magnesium which serves as a calcium blocker when excess calcium is in the system.

Click here for the full report (pdf file)

Melamine makes its way into US Infant Formula E-mail
Melamine makes its way into US Infant Formula

Comments by J. C. Spencer

Melamine compounds the importance for mother’s milk and the need to enhance baby formula with glyconutrients. The royal sugars I discuss in my book, Expand Your Mind - Improve Your Brain are found in human mother’s milk.

This toxic problem is caused by economics not reason. It is a matter of life and health for humans, especially infants. The toxin melamine is cheaper than powered milk. Glyconutrients are more expensive. Most of the poison powder filler melamine comes from China. Traces of melamine in US infant formula leaves a trail of which companies import some of their raw material. This is explained in this article. While the FDA is playing down the importance of the levels of melamine found in US infant formula, any amount is not good and while it normally does not cause instant death, it can cause long term damage to the vital organs especially the kidneys as reported in our last article on melamine.

Click here for the full report (pdf file)

Dangers of the Toxin Melamine Found in Food E-mail
Dangers of the Toxin Melamine Found in Food

Comments by J. C. Spencer

The toxin melamine found in foods, especially baby formula, has been a major concern lately. The melamine scandal has caused contamination of pet food and human foods made with powdered milk. A few have died and tens of thousands are sick.

The potentially deadly toxin is a white powder, looks like powdered milk, is cheaper than powdered milk. Powdered milk coming out of China has been laced with it . While glycomics teaches us that certain sugars are beneficial in removing toxins, we are to expose and halt toxins from ever entering the human body to the best of our abilities.

Short cuts in food production and marketing for sake of economics without regard for human life is the very reason we are in our health crisis. In one of my trips to India, I was told about how a worker had chipped little white rocks into rice size pieces to add to the rice to make it weigh more. My grandfather back in the early 1900s owned a country store. He told the story of some boys who bought from him some buckshot to fed to their geese to make them weigh more so they could sell them to my grandfather. The finger on the scale will destroy a society.

When toxins are intentionally added to food, that is criminal. But, if that toxin looks like and even has a molecular structure that fools the scientists, it can slip through normal detection. I have long contended that “identical molecules” can be different. A classic example, of course, is carbon. Coal/graphite and diamond are carbon, but each has different crystal structure. The structure, the bond, though it be slight, renders the molecule to have a totally different function. The angle of the bond, the positive or negative ion charge and the strength of that charge, and many factors concerning that environment yet to be discovered and understood, play roles in the functionality of molecules.

Following the articles on melamine in milk by David Bradley, Huang Yuanxi, Zhang Jing, Edward Wong, and others, you will be able to review how melamine tricked the scientists. Much of this extensive report comes out of China.

Click here for the full report (pdf file)

Healthful Sugars as Preventive Medicine E-mail
Healthful Sugars are Preventative Medicine

Doctors are calling healthful sugars PREVENTIVE MEDICINE. It is good that doctors today are thinking more about prevention. It becomes even better for the doctors who stop thinking in the pharmaceutical box. The article below is about how some of the doctors are thinking outside the pill box and calling great nutrition super foods to extend life.

More free services are added on our website to better benefit our friends. People who have never been to www.endowmentmed.org are often surprised that so much educational material is available through one website. You could literally invest 100 hours on the site gaining insight into glycomics, the science of sugars.

You can receive free Training in Lowering Healthcare Costs for individuals, families, and companies with new material coming soon. The many facets of Lowering Healthcare Costs can be found in our Sugar Science Forum which is accessible from the top and right hand side of our Home Page.

New discoveries in the use of sugars are making news daily. Glycoprotein technology is expanding rapidly and will continue to impact healthcare dramatically. Today on the NIH website at www.pubmed.gov when you type in glycoprotein, you will see 472,502 references to science papers. Drug companies are incorporating glycomics into the pharmaceutical industry. When these sugars are included in our nutrition the science becomes DISRUPTIVE because it operates outside the pill box. The bottom line is RESULTS, what works best, period. Our commitment to you is to help you educate others in what works best.

Today’s articles are about a doctor leaving his practice and starting a health restaurant and how Americans are Breeding a Future Generation of Overweight and Unhealthy Adults.

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Trehalose Found Instrumental in Hormonal Regulation and Gene Function in Plants E-mail
Trehalose Found Instrumental in Hormonal Regulation and Gene Function in Plants

Comments by J. C. Spencer

A German scientific paper reveals the importance of trehalose in plant cell wall biosynthesis, hormonal regulation and gene function. This science paper recently published in Plant Physiology discusses the role trehalose plays in hormonal regulation. The study made available through a grant from the Federal Ministry of Education and Research indicates the important role that trehalose may play in active nutrient uptake from the apoplastic space into the endosperm.

The Abstract discusses the transcriptional activation of nucleotide sugar metabolism and how it may be attributed to ascorbate synthesis and/or cell wall biosynthesis. These processes are potentially controlled by trehalose-6-P synthase/phosphatase, as suggested by expression of their respective genes.

Now, the Abstract:

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Trehalose - Hot Ingredient in Cosmeceutical & Neutraceutical Market - Has anti-aging functionality E-mail
Trehalose Becomes Hot Ingredient to Drive Cosmeceutical and Neutraceutical Market - Has anti-aging functionality

Comments by J. C. Spencer

Trehalose continues to be in the news as an additive for foods and cosmetics.  Research is verifying that trehalose has a unique functionality for significant cell protection.  A common response to overcoming cell stresses is the increased storage of trehalose and glycogen.  Structure of glucose molecules, their bonds, and the angle of their bonds trigger specific positive function including benefits for diabetics and a number of neurodegenerative diseases including Huntington’s, Alzheimer’s, and Parkinson’s.

Glycogen is the storage form of glucose in animals and humans which is analogous to the starch in plants. Glycogen is synthesized and stored mainly in the liver and the muscles. Structurally, glycogen is very similar to amylopectin with alpha acetal linkages, however, it has even more branching and more glucose units are present than in amylopectin. Various samples of glycogen have been measured at 1,700-600,000 units of glucose. The structure of glycogen consists of long polymer chains of glucose units connected by an alpha acetal linkage. Trehalose is a non-reducing disaccharide consisting of two glucose molecules bonded by an [alpha], [alpha] - 1, 1 glycosidic link which is stable at low pH conditions.

One of the most interesting recent discoveries is the possible role of trehalose and telomeres.  Telomeres are the DNA-protein complexes at the ends of eukaryotic chromosomes.  Telomeres are essential for maintaining genomic stability.  In the human body the telomeres keep getting shorter with age and when they reach a certain length, the cells cannot divide.

In my book Expand Your Mind - Improve Your Brain in Chapter 16 Rogue electrons: the enemy within, I say, “Damage to the DNA shortens the telomere.  The telomere is a structure containing a repeated DNA sequence found at both ends of every chromosome in the human body.  It was discovered in the 1990s that as a cell divides, the telomere keeps getting shorter.  When the telomere becomes a certain length, it sends a signal for the cell to no longer divide.

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New Treatment for Alzheimer’s & Huntington’s Diseases Relies on Addressing the Beta-Amyloid Pathway E-mail
New Treatment for Alzheimer’s and Huntington’s Diseases Relies on Addressing the Beta-Amyloid Pathway

Comments by J. C. Spencer

Ridding the brain of toxic amyloid plaques is viewed as a key target in slowing the course of Alzheimer's disease.  The amyloid pathway is THE MAIN HALLMARK OF ALZHEIMER'S DISEASE.  Here are two articles that deal with Alzheimer’s, Huntington’s, and the beta-amyloid pathway.  WHATEVER WORKS is what families with Alzheimer’s or Huntington’s members want to see.  Research has concluded what the problem is.  Throwing billions of dollars at the problem may not be the solution, but scientists are trying.  Part of the problem is that every drug, regardless of the hope it may help, adds more toxins to the body. 

Meanwhile, I suggest we look further at cutting healthcare costs by switching out regular sugar with a glyconutrient called trehalose.  The first article below is about GSK paying $28.5 million up front for a vaccine deal that may help address the beta-amyloid challenge.  The second article is an abstract from a published paper showing that the sugar trehalose may hold the answer for Alzheimer’s and Huntington’s disease by addressing the beta-amyloid challenge.

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