Easy Find It Page
Easy Find It
Use Our Mobile Site
Use Our Mobile Site
Share This Website
The Sugar Trehalose
Free NEWS Letter
Affiliate Program
Untitled Document

Already an Affiliate? Click on the link below to access your account-

Affiliate Login

Endowment Book Store
The Trehalose Store
Endowment Store Front
Support The Endowment
Enter Amount:
We Accept
VisaMaster CardAmerican ExpressDiscoverssl lock
Download Store

Download Store

Download 7 Free Newsletters Plus Other Educational Materials

Main Menu
Home
- - - - - - -
Inside the Human Cell
The Sugar Trehalose
- - - - - - -
Sugar Science Forum
Glycomics Training
Interactive Glycomics Brochure
NEWS
7 FREE NEWSletters
HOT Links of Interest
- - - - - - -
Contact Us
Disclaimer
Sitemap
Educational e-textbook
Chapter One

Chapter One

FREE Sneek Peek
Chapter One


Evaluation Forms

Huntington’s General
Health Evaluation
FORM for Trehalose
Nutritional Pilot Survey

Parkinson's General
Health Evaluation
FORM for Trehalose
Nutritional Pilot Survey

Alzheimer / Dementia
General Health Evaluation
FORM for Trehalose
Nutritional Pilot Survey

Diabetic Health Evaluation
FORM for Trehalose
Nutritional Pilot Survey

General Public Health
Evaluation FORM for
Trehalose Nutritional
Pilot Survey (For General
Public without Huntington’s,
Alzheimer’s, or Parkinson’s.)

Who's Online
We have 56 guests online
Breeding Ground for Monster Lab Using Transplanted Testis
http://www.livescience.com/php/mailtofriend.php?url=/othernews/060828_surrogate_rats.htmlhttps://www.space.com/php/members/register.phphttp://del.icio.us/posthttp://www.livescience.com/livescience_rss.htmlhttp://digg.com/submit?phase=2&url=http://www.livescience.com/othernews/060828_surrogate_rats.html&title=Rats+Born+to+Mice+in+Bizarre+Lab+Work&bodytext=The+breakthrough+suggests+a+way+to+save+endangered+species.+As+a+strange+aside,+it+produced+rats+that+glow+green.
Rats Born to Mice in Bizarre Lab Work
By Charles Q. Choi
Special to LiveScience
posted: 28 August 2006
05:00 pm ET


In lab rats, "Who's your daddy?" can now yield a surprising answer. Scientists have generated rats from mice that developed rat sperm.

The breakthrough marks the first time researchers produced healthy offspring [Photo] from sperm cells fostered in a different species. The hope is this method could help generate sperm from endangered species or prize bulls.

A decade ago, scientists successfully developed sperm in one animal that had come from cells in another. Researchers began by growing rat sperm in mice, and proceeded to foster sperm from hamsters, rabbits, pigs, bulls and humans in mice as well.

However, until now it remained unknown whether any of these sperm were fertile. In several instances they developed abnormally in their foreign hosts.

The breakthrough

Reproductive biologist Takashi Shinohara at Kyoto University in Japan and his colleagues first began with rats genetically engineered to produce a green fluorescent protein. Their cells and progeny would thus prove easy to recognize. Shinohara and his colleagues then removed the stem cells that sperm arise from in the rats and implanted them into testicles of mice.

The scientists collected fluorescent green rat sperm from the mice and injected them into rat eggs. Successfully fertilized eggs were transferred into surrogate rat mothers.

None of the fluorescent green rat pups bornyes, they are really green—displayed any abnormalities, genetic or otherwise. Moreover, they grew up to become fertile adults.

Breeders use sperm taken from prize livestock to produce offspring that hopefully possess the same valuable traits. Scientists also use sperm to help endangered species generate progeny. The hope is that mice or other lab animals can grow sperm of livestock or endangered species while "saving space, food and in general being easier to take care of," Shinohara told LiveScience.

Human applications

The capability this opens up to study human sperm generated using this method could lead to novel contraceptives, Shinohara added, or in studying what contaminants are toxic to male reproduction.

While this breakthrough raises the possibility of growing human sperm in other animals to generate viable human offspring, "it is not a good idea," Shinohara said. Besides the ethical issues, he noted there are viruses present in animals that could write themselves into genetic codes of the human sperm.

Shinohara and his colleagues reported their findings online Aug. 28 via the Proceedings of the National Academy of Sciences.




> Click to View



> Click to View